Vesugen Technical Overview
Vesugen is one of the shortest members of the Khavinson peptide bioregulator series, a family of two-residue to four-residue sequences assembled largely from lysine, glutamic acid, aspartic acid, alanine, and glycine. Its three residues carry one basic side chain and two acidic side chains, which gives the molecule a high charge density and ready water solubility.
Research associated with KED centers on vascular endothelial cell cultures, transcript and protein expression profiling, and cell culture models of aging. Laboratory reports place it alongside the AEDG and EDR short peptides as a sequence studied for modeled interactions with promoter-region DNA.
Compound Specifications
| Property | Value |
|---|---|
| CAS Number | 204271-66-9 |
| PubChem CID | 87571363 |
| ChEBI ID | CHEBI:159909 |
| Molecular Formula | C₁₅H₂₆N₄O₈ |
| Molecular Weight | 390.39 g/mol |
| Monoisotopic Mass | 390.17506 Da |
| Amino Acid Sequence | H-Lys-Glu-Asp-OH (one-letter: KED) |
| Sequence Length | 3 residues |
| IUPAC Name | (2S)-2-[[(2S)-4-carboxy-2-[[(2S)-2,6-diaminohexanoyl]amino]butanoyl]amino]butanedioic acid |
| InChIKey | LLSUNJYOSCOOEB-GUBZILKMSA-N |
| Canonical SMILES | C(CCN)CC@@HN |
| Synonyms | Vesugen, KED, Lys-Glu-Asp, L-lysyl-L-glutamyl-L-aspartic acid, lysyl-glutamyl-aspartic acid |
| Source | Synthetic |
| Purity | ≥99% (HPLC) |
| Appearance | Lyophilized white powder |
| Solubility | Soluble in water |
| Vial Size | 20 mg |
| Storage | -20°C, protect from light |
Storage and Handling
- Store the lyophilized compound at -20°C, protected from light.
- After reconstitution with bacteriostatic water, store at 2°C to 8°C and use promptly.
- Avoid repeated freeze-thaw cycles, which degrade short peptides in solution.
- Maintain aseptic handling to preserve compound integrity.
Lyophilized Format
This compound ships in lyophilized (freeze-dried) form. Freeze-drying supports long-term storage stability and preserves compound integrity. No fillers are added.
Research Use Disclaimer
Vesugen 20mg is supplied for research use only. It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. By purchasing, the buyer confirms the compound will be used solely for in vitro research.
Frequently Asked Questions
What Is Vesugen?
Vesugen 20mg is a synthetic tripeptide with the sequence Lys-Glu-Asp, supplied as a lyophilized powder in a 20 mg glass vial for laboratory research. It is one of the short peptide bioregulators characterized in the Khavinson research literature, where it appears under the abbreviation KED.
What Is the Molecular Weight of Vesugen?
Vesugen has a molecular weight of 390.39 g/mol and the molecular formula C₁₅H₂₆N₄O₈. Its monoisotopic mass is 390.17506 Da, recorded under PubChem CID 87571363.
What Is the Amino Acid Sequence of Vesugen?
Vesugen has the three-residue sequence H-Lys-Glu-Asp-OH, written KED in one-letter notation. That sequence, not the product name, is the term indexed by PubMed and the chemical structure databases.
How Should Vesugen Be Stored?
Vesugen should be stored lyophilized at -20°C and protected from light. Once reconstituted, hold it at 2°C to 8°C, use it promptly, and avoid repeated freeze-thaw cycles.
How Is the Purity of Vesugen Verified?
Vesugen purity is verified at 99% or higher through independent third-party laboratory analysis using liquid chromatography with mass spectrometry. Every vial from BioLongevity Labs ships with a batch-specific certificate of analysis tied to that lot.
