What Is BioMind?
BioMind is a three-in-one neurocognitive research compound designed to explore neuroplasticity, cognitive function, and neuroprotection. It combines J-147, Dihexa, and Noopept, which individually and synergistically support brain health, memory formation, and resilience against neurodegeneration.
- J-147 (10mg per capsule): A neuroprotective compound that modulates mitochondrial function and increases BDNF, reducing neuroinflammation and oxidative stress while improving cognitive function.
- Dihexa (10mg per capsule): A synaptic growth promoter that enhances neural connectivity and repair, mimicking natural neurotrophic factors like HGF.
- Noopept (10mg per capsule): A dipeptide nootropic that modulates neurotransmission, improves memory retention, and protects neurons from excitotoxicity.
Together, these compounds offer a unique research opportunity to study cognitive resilience, neurodegenerative disease mechanisms, and neural regeneration in preclinical models.
BioMind Research Compounds and Mechanisms
- J-147 – Mitochondrial Modulation and Neuroprotection
J-147 is a novel neuroprotective agent that enhances mitochondrial function, promotes cellular longevity pathways, and protects against oxidative stress.
- Increases levels of brain-derived neurotrophic factor (BDNF), promoting neuroplasticity and cognitive resilience.
- Modulates AMPK/mTOR pathways, which are linked to cellular energy regulation and anti-aging effects.
- Protects neurons from oxidative stress and excitotoxicity, reducing markers of neuroinflammation and neuronal death.
- Improves memory and learning ability in preclinical models of Alzheimer’s disease and cognitive decline.
- Crosses the blood-brain barrier efficiently, enabling direct action on brain mitochondria and synapses.
Research has demonstrated J-147’s ability to reverse cognitive deficits, reduce amyloid plaque burden, and enhance synaptic density, making it a valuable tool for studying neurodegeneration, cognitive enhancement, and longevity pathways.
- Dihexa – Synaptogenesis and Neural Repair
Dihexa is a synthetic neurotrophic compound derived from angiotensin IV, designed to stimulate synapse formation and neural repair.
- Binds and activates hepatocyte growth factor (HGF) receptors, promoting synaptogenesis and neural connectivity.
- Enhances long-term potentiation (LTP), a fundamental mechanism for memory consolidation and learning.
- Protects neurons from glial activation, neuroinflammation, and oxidative stress.
- Crosses the blood-brain barrier and remains active in neural tissue for extended periods.
- Has demonstrated restorative effects in Alzheimer’s disease models, showing memory recovery and increased synaptic density.
Dihexa’s unique mechanism makes it a valuable research tool for exploring cognitive resilience, neuroregeneration, and neurodegenerative disease pathways.
- Noopept – Cognitive Enhancement and Neuroprotection
Noopept is a dipeptide-derived nootropic with rapid absorption and neuroprotective effects.
- Modulates AMPA and NMDA glutamate receptors, supporting synaptic signaling and plasticity.
- Enhances acetylcholine transmission, contributing to improved focus, memory, and recall.
- Increases NGF (nerve growth factor) and BDNF, reinforcing neuronal survival and growth.
- Provides anti-inflammatory and antioxidant effects, reducing neuronal damage from stressors.
- Has been shown to reverse memory deficits in models of neurodegeneration and aging.
Noopept’s short half-life and rapid neuroactive conversion make it a prime candidate for investigating acute cognitive enhancement, synaptic signaling, and neuroprotection in preclinical settings.
Synergistic Effects of J-147, Dihexa, and Noopept
BioMind contains three complementary neuroactive compounds that interact to support cognitive enhancement and neuroprotection:
- J-147 increases BDNF and promotes mitochondrial function, creating a favorable environment for synaptic plasticity.
- Dihexa enhances neural connectivity and synaptic repair, making new neural pathways more resilient.
- Noopept amplifies neurotransmission efficiency, improving short-term memory and cognitive processing.
Together, these compounds provide a unique opportunity to study neurodegeneration, cognitive enhancement, and neuronal repair mechanisms in a multi-target research framework.
Molecular Structure and Data
J-147
- Chemical Name: N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N’-(3-methoxybenzyl)hydrazine
- CAS Number: 1146963-51-0
- Molecular Formula: C₁₈H₁₇F₃N₂O₂
- Molecular Weight: 350.34 g/mol
Dihexa
- Chemical Name: N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide
- CAS Number: 1401708-83-5
- Molecular Formula: C₂₇H₄₄N₄O₅
- Molecular Weight: 504.7 g/mol
Noopept
- Chemical Name: N-phenylacetyl-L-prolylglycine ethyl ester
- CAS Number: 157115-85-0
- Molecular Formula: C₁₇H₂₂N₂O₄
Molecular Weight: 318.4 g/mol
