Vilon Technical Overview
Vilon is the research designation for the KE dipeptide, one of the shortest sequences in the Khavinson bioregulator series. At two residues it sits at the low end of the peptide size range, which is the property that makes it a frequent subject of molecular modeling work on how very short sequences associate with double-stranded DNA.
The compound is produced synthetically rather than extracted, so the material supplied for research is a defined single sequence rather than a tissue fraction. This distinction matters in laboratory work, because the historical thymus-derived preparations that preceded it were multi-component extracts.
Research interest in Vilon centers on epigenetic regulation, cultured immune-cell models, and cell-aging models. It is frequently studied alongside related short sequences such as Epitalon (AEDG) and KED for comparison across the same assay panels.
Compound Specifications
| Property | Value |
|---|---|
| CAS Number | 45234-02-4 |
| PubChem CID | 7010502 |
| Chemical Name (IUPAC) | (2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]pentanedioic acid |
| Molecular Formula | C₁₁H₂₁N₃O₅ |
| Molecular Weight | 275.30 g/mol |
| Monoisotopic / Exact Mass | 275.14812 Da |
| InChIKey | UGTZHPSKYRIGRJ-YUMQZZPRSA-N |
| Amino Acid Sequence | Lys-Glu (one-letter: KE) |
| Sequence Length | 2 residues |
| Source | Synthetic |
| Synonyms | Vilon, KE dipeptide, Lys-Glu, Lysylglutamic acid, N-L-Lysyl-L-glutamic acid, L-Lysyl-L-glutamic acid, H-Lys-Glu-OH, Normophthal, AB-0 peptide |
| Purity | ≥99% (HPLC) |
| Appearance | Lyophilized white powder |
| Solubility | Soluble in water |
| Vial Size | 20 mg |
| Storage | -20°C, protect from light |
Storage and Handling
- Store the lyophilized compound at -20°C, protected from light.
- After reconstitution, store at 2°C to 8°C and use promptly.
- Maintain aseptic handling to preserve compound integrity.
- Avoid repeated freeze-thaw cycles of reconstituted material.
Lyophilized Format
This compound ships in lyophilized (freeze-dried) form. Freeze-drying supports long-term storage stability and preserves compound integrity. No fillers are added.
Research Use Disclaimer
Vilon is supplied for research use only. It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. By purchasing, the buyer confirms the compound will be used solely for in vitro research.
Frequently Asked Questions
What Is Vilon and What Class of Compound Is It?
Vilon is a synthetic dipeptide with the sequence Lys-Glu (KE), classified as a Khavinson short peptide bioregulator. It carries CAS number 45234-02-4 and PubChem CID 7010502.
What Is the Molecular Weight of Vilon?
Vilon has a molecular weight of 275.30 g/mol and a molecular formula of C₁₁H₂₁N₃O₅. Its monoisotopic mass of 275.14812 Da is the value used for LC-MS confirmation.
How Is Vilon Supplied and Stored?
Vilon ships as a lyophilized white powder in a 20mg vial and should be held at -20°C protected from light. Reconstituted material is kept refrigerated and used promptly.
How Is the Purity of Vilon Verified?
Vilon is tested to ≥99% purity by HPLC, with identity confirmed by mass spectrometry against the compound’s monoisotopic mass. Third-party analytical documentation accompanies each lot.
What Research Areas Is Vilon Studied In?
Vilon is studied in laboratory models of gene expression regulation, peptide-DNA binding, cultured immune-cell signaling, and replicative cell aging. All of these are in vitro and animal-model research contexts.
