Vilon Peptide Description
Vilon is a Khavinson peptide bioregulator that functions as a potent research compound targeting thymus-related immune system pathways. Composed of two amino acids (Lys-Glu), this anti-aging peptide demonstrates measurable effects in laboratory studies. Research indicates Vilon may help modulate lymphocyte responses and heterochromatin organization in vitro.
Studies examining the effect of Vilon show potential applications in tumor research and immune regulation investigations. As one of the shortest active peptide bioregulators, Vilon peptide may provide researchers with insights into cellular aging mechanisms. For research use only.
Peptide Specifications
| Property |
Value |
| Peptide Sequence |
L-Lys-L-Glu |
| Molecular Formula |
C₁₁H₂₁N₃O₅ |
| Molecular Weight |
275.3 g/mol |
| CAS Number |
45234-02-4 |
| PubChem CID |
7010502 |
| Synonyms |
Lysylglutamic acid, N-L-Lysyl-L-glutamic acid, H-Lys-Glu-OH, Lysyl glutamate, KE |
Vilon Bioregulator Research
Vilon peptide represents one of the shortest bioactive compounds studied in laboratory research, consisting of just two amino acids (Lys-Glu). Scientific investigations reveal this dipeptide demonstrates measurable effects across multiple cellular pathways in controlled research environments.
Gene Expression Regulation
Laboratory studies show KE peptide binds directly to double-stranded DNA in cell nuclei, specifically targeting GCGC sequences found in 642 gene promoters[1]. This binding mechanism allows the peptide to regulate multiple genes simultaneously in research cell cultures[2].
Research demonstrates the peptide interacts with histone proteins, potentially altering chromatin structure in laboratory conditions. These modifications may influence gene accessibility and transcription factor binding in controlled studies[1].
Immune System Modulation
In vitro experiments reveal Vilon modulates cytokine production in cultured immune cells. The peptide specifically targets the CHUK gene, which encodes components for NF-κB signaling pathway regulation[1].
Laboratory research shows the compound stimulates T-cell differentiation and promotes CD4 and CD5 molecule expression in thymic cell cultures. Studies demonstrate up to 6-fold reduction in inflammatory cytokine synthesis in stimulated cell preparations[2].
Cellular Aging Research
Research indicates Vilon normalizes telomere length in stimulated lymphocyte cultures across different age groups in laboratory conditions. The peptide increases euchromatin proportion while decreasing heterochromatin in aging cell models[2].
Gene expression analysis reveals the compound regulates aging-related genes including IGF1, FOXO1, TERT, and NFκB in mesenchymal stem cell cultures. Laboratory studies show reduced apoptosis markers in aging cell preparations treated with the peptide[2].
Cardiovascular Research Applications
Studies demonstrate Vilon influences ACE2 gene expression, which encodes angiotensin-converting enzyme 2 in cardiovascular research models. The peptide also regulates AKT1 and AKT2 genes linked to cellular survival and angiogenesis pathways[1].
Metabolic and Stress Response Studies
Research shows the peptide affects heat shock protein synthesis and cellular stress response mechanisms in laboratory conditions. The compound influences genes encoding proteins involved in energy production and oxidative stress tolerance[2].
Laboratory investigations reveal Vilon regulates matrix metalloproteinase-9 expression and increases Ki-67 synthesis in cultured fibroblast preparations. These findings suggest potential applications in tissue repair research models[2].
References
- N. Linkova et al., “The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19,” MDPI AG, Aug. 2023. doi: 10.3390/ijms241713377. Available: https://doi.org/10.3390/ijms241713377
- V. Kh. Khavinson, N. S. Linkova, N. I. Chalisova, and O. M. Ivko, “The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity,” Pleiades Publishing Ltd, Jul. 2021. doi: 10.1134/s2079086421040046. Available: https://doi.org/10.1134/s2079086421040046
Certificate of Analysis (COA) for Every Batch
A Certificate of Analysis (COA) is a document that verifies a compound’s identity, purity, and batch quality through independent laboratory testing. Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol.
Each COA reports results from third-party laboratory analysis, including:
- Ultra-high-performance liquid chromatography with mass spectrometry (UHPLC-MS) for purity, typically confirmed at 99% or higher
- Mass identification for molecular confirmation and content quantitation
- Endotoxin quantitation by Limulus amebocyte lysate (LAL) assay where applicable
- Visual and physical characterization of the finished material
How to verify a COA independently
Every certificate can be checked against the issuing laboratory’s own records, not just the copy hosted here. Verification does not depend on BioLongevity Labs.
- MDx BioAnalytical Laboratory certificates carry a QC tracking number and a search code. Newer certificates also carry a QR code. Scan the code, or enter the search code at mdxbiolabs.com, to pull the official record.
- BioRegen reports of analysis carry a Report ID and a Validation Key. Scan the QR code on the certificate to open the official record, or reference both identifiers when contacting the laboratory at the address printed on the report.
- SafeCert Labs certificates, which appear on a number of earlier batches, carry a COA number and the signature of the reporting chemist. Reference that number when requesting confirmation from the laboratory directly.
Batches are frequently tested by both laboratories independently. When two certificates exist for the same lot, each one resolves at its own issuing laboratory, which lets a researcher confirm the same material twice through two unrelated sources.
COAs are sourced from independent certified labs rather than in-house testing alone, giving researchers a verifiable record of molecular integrity for each batch. All compounds are supplied for research use only.
Review the COAs for this batch below, or browse the full COA library.
Vilon (261413)
Endotoxin Vilon
Vilon (11352)
Vilon (251536)
Vilon (251536E)
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